Camera-traps (CTs) are an increasingly popular tool for wildlife survey and monitoring. Estimating relative abundance in unmarked species is often done using detection rate as an index of relative abundance, which assumes a positive linear relationship with true abundance. This assumption may be violated if movement behavior varies with density, but the degree to which movement is density-dependent across taxa is unclear. The potential confounding of population-level relative abundance indices by movement depends on how regularly, and by what magnitude, movement rate and home-range size vary with density. We conducted a systematic review and meta-analysis to quantify relationships between movement rate, home range size, and density, across terrestrial mammalian taxa. We then simulated animal movements and CT sampling to test the effect of contrasting movement scenarios on CT detection rates. Overall, movement rate and home range size were negatively correlated with density and positively correlated with one another. The strength of the relationships varied significantly between taxa and populations. In simulations, detection rates were related to true abundance but underestimated change, particularly for slower moving species with small home ranges. In situations where animal space use changes markedly with density, we estimate that up to thirty percent of a true change in abundance may be missed due to the confounding effect of movement, making trend estimation more difficult. The common assumption that movement remains constant across densities is therefore violated across a wide range of mammal species. When studying unmarked species using CT detection rates, researchers and managers should consider that such indices of relative abundance reflect both density and movement. Practitioners interpreting changes in detection rates should be aware that observed differences may be biased low relative to true changes in abundance, and that further information on animal movement may be required to make robust inferences on population trends.