Borealis
McMullen, Carrie K.;
Sargeant, Jan M.;
Kelton, David F.;
O'Connor, Annette M.;
Reedman, Cassandra N.;
Hu, Dapeng;
Glanville, Julie;
Wood, Hannah;
Winder, Charlotte B.
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2021-09-27
This data is an ancillary analysis conducted for the systematic review and network meta-analysis to investigate the relative efficacy of antimicrobials to cure existing intramammary infections in dry cows. This ancillary data was used to analyze the results of trials published between 1990 - 2019 because eradication programs for Streptococcus agalactiae, a bacterium very susceptible to penicillin products, were implemented in the 1980s and achieved low levels of this pathogen in dairy herds (Makovec and Ruegg, 2003; Keefe, 2012), such that penicillin products could have an inflated measure of cure of existing IMI within the network in studies prior to 1990. This analysis was not pre-specified in the protocol, nor did it provide inferences that differed from the full network meta-analysis.